I do find that if I have foods containing tryptophan such as turkey meat, I want to fall asleep! how much tryptophan to take with collagen. So theres no guarantee that your collagen supplement contains the type or amount of collagen the label says it does. I am intrigued and dont even know if using collagen would raise blood collagen levels. Do I need to take pharmagaba or GABA? Since collagen powders and other collagen supplements are usually made from animals, they might contain heavy metals or other toxins that can collect in animals bones. She suggested that i mix protien into my collagen. But i was confused when I saw many articles about collagen improving sleep but from this i can see its the missing tryptophan? More on that here https://www.everywomanover29.com/blog/oxalate-crystal-disease-dietary-oxalates-and-pain-the-research-questions/. Both times I had to call 911. Thank you Trudy for your prompt response. I ordered this through Amazon and so many people recommend this product. Tryptophan has also been found to stimulate the release of growth hormones and even reduce food cravings for carbohydrates in some cases. To be safe, I have decided to stop my collagen supplements. There is some concern, however, about taking tryptophan-containing supplements with SSRIs (selective serotonin reuptake inhibitors) like Lexapro. (If there is an issue.) Trudy, another issue about collagen, at least for some of us, is the blood pressure connection. Simply put, adding tryptophan to collagen jeopardizes efficacy and safety. Hoping you already figured this out. I've been taking a lot more bacopa than you apparently but haven't experienced the mood issues that you describe. Collagen helps keep the shape of your arteries and blood vessels. Collagen can be found in all animal muscle tissue (not organ tissue), bone broth, egg whites and spirulina. I add a tablespoon of raw honey and tart cherry juice concentrate (for its anti-inflammatory properties). I was told that I had an allergic reaction to penicillin when I was a child. Research suggests that most healthy adults consume around 900 to 1000 milligrams of tryptophan daily. No idea whether or not that's a good thing, but its byproduct isn't so great. Together with bacopa and ginkgo you have the fab four. Should I take a collagen supplement? - MD Anderson Cancer Center As we age or go through other major changes, our body's natural collagen production begins to decline, which may lead to the appearance of fine lines and sagging skin. Anne ACTH activates your adrenal glands to increase cortisol production. The amount added to collagen supplements is generally low, around 30-80 per serving. how much tryptophan to take with collagen. You're already getting enough tryptophan. Its fiber-like structure is used to make connective tissue. Collagen protein displays a low indispensable amino acid profile, yet as a functional food, collagen is a source of physiologically active peptides and conditionally indispensable amino acids that have the potential to optimize health and address physiological needs posed by aging and exercise. After researching i discovered it was the collagen. When Is the Best Time to Take Collagen? Here's the Answer Insomnia not so bad, I do wake a lot during the night. Erythritol: Is This Healthy Sweetener the Real Deal? https://www.everywomanover29.com/blog/collagen-gelatin-lower-serotonin-increase-anxiety-depression/, I even mention there are also quite a few naysayers. Is there such a thing as too much collagen powder? Medical Content Reviewed By HelloPharmacist The most effective anxiety treatment I've been using for over a year now are pro/prebiotics. Thats because factors like someones age, weight/body composition, level of activity and digestive/intestinal health all affect how much is absorbed and used. When you shop for. Your will wake up feeling refreshed the next day. Type I, which gives strength to your skin, bones, ligaments, and tendons, Type II, which makes up the flexible cartilage that helps support your joints, Type III, found in your internal organs, blood vessels, and muscles, Type V, which is present in your corneas as well as some layers of skin and hair, : Collagen Structure and Stability., : Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials., Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails, The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials., : A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study, Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men, Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women A Randomized Controlled Study, Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance., The Journal of Clinical and Aesthetic Dermatology, : A Double-blind, Placebo-controlled Study Evaluating the Efficacy of an Oral Supplement in Women with Self-perceived Thinning Hair., : Decreased Collagen Production in Chronologically Aged Skin., : Collagen peptide supplementation in combination with resistance training, improves body composition and increases muscle strength in elderly sarcopenic men: a randomized controlled trial., : Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature.. It helps to make tissues strong and resilient, able to withstand stretching. Collagen aids in healing and repairing damaged bones and cartilage. I have such a sense of relief knowing this could be such a simple fix. how much tryptophan to take with collagenwhich of the following expressions are polynomials. If its the oxalate issues it can take longer and same with histamine. One of the things often overlooked when people are trying to improve their overall health, have more energy and sleep better is the importance of obtaining enough amino acids from differentprotein foods. Everything Im reading here makes perfect sense. Here are some more things to know if you are going to take melatonin. How long did it take for you to feel normal again, after stopping the collagen supplements ?? The added concern about high blood pressure really concerns me as well. Anytime multiple drugs/supplements affect serotonin, there is an increased risk of a rare, but serious condition known as serotonin syndrome. The side effects are real, and for me quite severe. It's not a problem as long as you take it, but you will get mild withdrawals. The mechanism behind the antidepressant effects of Lexapro isn't fully understood but involves both increases in available serotonin in certain parts of the brain as well as a change in the balance of serotonin receptors in the brain. At Levels, we recommend you start with a single 10-gram dose per day, then consider adding additional doses based on your results. There's not necessarily a best time of day to take collagen protein, at least not according to current studies. feeling drowsy or light-headed; dry mouth, heartburn, burping, gas; stomach pain, nausea, vomiting, diarrhea; weakness, lack of coordination; blurred vision; headache; or sexual problems. How high did it go and did it drop when you stopped collagen (and how quickly)? I use the amino acid questionnaire to assess for low serotonin and trials of tryptophan or 5-HTP https://www.everywomanover29.com/blog/amino-acids-mood-questionnaire-from-the-antianxiety-food-solution/ There is also a platelet serotonin test but I seldom use it. In conclusion, treatment with a herbal extract of radix valerianae demonstrated positive effects on sleep structure and sleep perception of insomnia patients, and can therefore be recommended for the treatment of patients with mild psychophysiological insomnia. The green tea and ginseng are not interchangeable, tea is not a GABAb antagonist. Taking Collagen That Contains Tryptophan And Tyrosine With Lexapro - Walrus Should I stop taking all 3 at once & is there a collagen with added Tryptophan out there?!?! Your will wake up feeling refreshed the next day. Recent blood test indicated everything was right but I havent felt right for a long time For susceptible folks dietary tryptophan is not enough. 2. Thanks!! Serotonin increases your adrenocorticotropic hormone (ACTH). Is there something else I can benefit from besides the collagen? This is not a complete list of side effects and others may occur. Collagen also helps to maintain the resistance, elasticity and mobility of joints and connective tissue. Throughout the following months, I started to get more and more back to normal. peter macari age. There is more concern with the amount of tryptophan combined in stand-alone dietary supplements, and even then, the risk of serotonin syndrome occurring is low. Again, tryptophan is an essential amino acid, and we consume it in our diet regularly (we have to, as our bodies cannot synthesize it), so in a sense, everyone taking Lexapro is already taking it in combination with tryptophan. The amount added to collagen supplements is generally low, around 30-80 per serving. Is it possible for collagen supplementation to cause a sensitivity to sulfur? I was not sure if there was a correlation between collagen and insomnia until I read your blog. Tryptophan is an essential amino acid. Dominic I was hoping Id get used to it but its been nearly a week. There are some collagen products with tryptophan but I prefer using tryptophan separately so doses can be controlled and adjusted up or down. I found them both on bulksupplements, ginseng extract and ginko, but you use tea instead? Im afraid I dont have an answer for you but I would advise checking out other ingredients for toxicity on EWG Skindeep site https://www.ewg.org/skindeep/. . Collagen supplementation benefits the body in two ways: It's bioactive and supplies the body with key amino acids. Thank you! You can help your body produce more collagen by eating lots of glycine- and proline-rich foods like chicken, beef, fish, dairy, eggs, and beans. Linda Collagen is responsible for the health of our hair, skin, nails, blood vessels, digestive system, and musculoskeletal system. I STOPPED TAKING FOR ONE MONTH AND REALIZED, I GOT BACK TO NORMALTHEN NOT REALIZING IT MAY HAVE CAUSE THE PROBLEM, I STARTED TAKING ONE SMALL SCOOP A DAY, WHAM, WITHIN ONE WEEK, SCREWED UP,.NOT SLEEPING AND WAKING UP OUT OF FRUSTRATION AT 3 AM IN THE MORNING..BAD STUFF FOR US..IT ACTUALLY DESTROYED MY FAMILY AND THEY ARE VERY, VERY UPSET WITH ME CAUSE RAMIFICATIONS OF NO SLEEP, ANXIETY HAS CAUSED THEM MAJOR HARM MENTALLY, PHYSICALLY AND CAUSED THEM TO MAKE UNRASH DECISIONS DUE TO BEING UNSTABLE.. Adam I see they have a COA there but I like seeing brands tested on Labdoor. Important to note, that if your body is fighting inflammation, try mixing the powder tryptophan to a tbsp of collagen in some warm water, this will help it pass the blood-brain barrier without competing with certain cytokines cause by inflammation, learned this trick from a biochemist names Steve Fowkes. We have to rely on food or supplements such as . Hi, I do have osteoarthritis and hate the aging process. Your body then puts these amino acids together to form new proteins. It mostly affected new folks who were commenting for the first time but its hopefully resolved now. 0 Reply More posts you may like r/FODMAPS Join 1 yr. ago Each scoop provides 10 grams of collagen along with Vitamin C, Tryptophan, Pineapple and Papaya. Its possible you experienced low serotonin effects (feelings of doom, anxiety, insomnia) + a histamine and/or glutamate reaction (severe anxiety, chest pain, dizziness, nausea, headache, shortness of breath, flushing, inability to regulate my temperature, and insomnia, rushes of adrenalin). Thanks for reaching out and I hope this was helpful! Ingesting collagen as your main form of protein can potentially lead to a deficit in tryptophan. Many thanks, Ann Doesnt glutamic acid/glutamate worsen anxiety and ocd issues? It might be worth noting that I am a hyperthyroid patient, taking a low dose of methimazole, an anti-thyroid drug. New to me the connection and testing collagen in blood for this purpose. I woke suddenly, had racing heartbeat, anxiety, accelerated breathing rate, excessive drynes. Then I happened to Google the topic of collagen and discovered this website, and was amazed to read about so many others whod experienced the same issues. I add a tablespoon of raw honey and tart cherry juice concentrate (for its anti-inflammatory properties). I'm on the red ginseng, currently. Always make sure you buy supplements from a reputable source.. For the best results and strongest calming effects, combine the protein foods below with a small serving of unrefinedcarbohydrates (like potatoes, veggies, beans or even fruit) in order to help tryptophan cross the blood-brain barrier, where it can boost serotonin levels. I've read in other places about Steve Fowkes' recommendation. Here's the full transcript of what he's talking about:https://www.bulletpr-fowkes-part-2/. Collagen peptides act as messengers to the cells and trigger the synthesis and reorganization of new collagen fibers, therefore supporting skin, bone and joint tissue structures.**. * Summary The science is still emerging for collagen peptides. Can I Use Collagen While Pregnant? - Vital Proteins You can take collagen powder by mixing it into smoothies, shakes, baked goods, soups, or even your coffee or tea.. http://www.tonu.org/2016/11/05/glyphosate-glycine/ Glyphosate is dangerous because it mimics glycine Samsel and Seneff Glycine is the most important amino-acid in collagen. I am on an SSRI but am experiencing intense anxiety and stimulation from the collagen. But scientists are still debating the benefits of collagen powder and other collagen supplements. Don't add me to the active users list. Collagen is the most abundant protein in the body. If you have yet to sign up, please do come and join us and learn. That's a long list. Thank you for publishing this information so that I can see that I am not alone. I believe it because I just Googled if collagen can cause insomnia amd according to this report it can. I am mind blown. Trying to find a more affordable source, I posted in another thread about that. I got to thinking today, maybe it is the collagen. In this 2016 study, the role of amino acids in the blood in relation to attention-deficit/hyperactivity disorder (ADHD) was examined. 07/03/2022 . The tea is a lot more invigorating, ginkgo is so subtle and behind the scenes (more than ginseng), but on a quiet day, down by the stream.. you can feel it working. Tammy An important byproduct of tryptophan is 5HTP (5-hyrdoxytryptophan), whichworks in the brain and central nervous system to boost feelings of well-being, connection and safety. A product called gelatinheath collagen. Sitemap, FIRST & ONLY Multi Collagen NSF Certified, Is Collagen a Complete Protein? EDIT: I looked up who Steve Fowkes is, he doesn't have a good rep on science based medicine, which casts doubt on anything he's saying here. To alternate days, of 5-HT and GABA, is one idea for maintenance insomnia. I've only been taking 400mg of theanine at night for most of the year, only sometimes do I take it during the day or before improv and really only today did I use it (200mg) before playing Overwatch. Trudy, I started taking collagen 3 months ago in a pill form( Organika bio cell brand). Collagen Can Boost Your Thyroid Hormone Conversion by Lowering Cortisol In the summit interview we also talk about bone broths and a step-by-step approach to figure out if your issue with collagen is one of the following and what to do about it: This is one of 4 interviews I do on the summit. Also, feelings of doom and that something was terribly wrong even though nothing in my life was really any different. Its not a matter of clearing collagen but rather addressing the effects. I thought I saw a comment on this on your site, re marine collagen. Staci Should i take tryptophan with collagen? Explained by Sharing Culture It also by contrast did not give me the hangover the next day, the headache or the brain fog. HAS CAUSED ANXIETY IN ALL MY FAMILY MEMBERS SO BAD, TWO HAVE HAD NERVOUS BREAKDOWNS FROM LACK OF SLEEP. So i started Vital Proteins collagen , methylated b-12 (im mthfr c677t) and hair skin nail biotin (b7) vitamins in the morning . how much tryptophan to take with collagen - frazzao.com.br Twitter. Vivien Correct for most people its the fact that collagen doesnt contain tryptophan and leads to lowered serotonin and adversely impacting sleep (and increasing anxiety in some). I should add that I was taking bovine collagen supplements and I wonder if I would have had the same outcome with MARINE collagen instead or is there no difference? Until then let us know how you do use collagen or gelatin and if youve noticed any mood issues, increased anxiety or insomnia? Should i take tryptophan with collagen? - nskfb.hioctanefuel.com There can be large differences in the actual needs of individuals when it comes to daily tryptophan intake. Heres the key: Tryptophan, chemistry behind collagen is just like other proteins long chains of amino acids, same tryptophan found in your Thanksgiving turkey, theres no best time time to take collagen, you should get your overall nutrition from food first, then supplement, Product Comparison: Unflavored Every Day vs Unflavored NSF Certified, The Collagen Handbook for Vegans & Vegetarians, Collagen vs Collagen Peptides (aka Hydrolyzed Collagen! The study showed that these collagen-supplementing athletes experienced little to no joint pain and inflammation after training. For example, whey protein has a PDCAAS of 1 [97], whereas hydrolyzed. My response to Huffington Post blog, Vagus nerve rehab with GABA, breathing, humming, gargling and key nutrients, Sundowning in Alzheimers and dementia: melatonin/tryptophan for the agitation, restlessness, anxiety, disturbed sleep and aggression, GABA and Silexan (an oral lavender product) for anxiety, panic attacks, agoraphobia, insomnia and stressful events like travel/social events, GABA Calm is a game changer for husbands sound and tactile hypersensitivity, significant coordination problems and his anxiety, A case of enterobiasis presenting as post-traumatic-stress-disorder / PTSD (i.e. denver museum of nature and science prehistoric journey. I would like to start using a collagen cream on my skin for it to become less saggy. The Antianxiety Food Solution: How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood and End Cravings, http://www.tonu.org/2016/11/05/glyphosate-glycine/, https://www.everywomanover29.com/blog/amino-acids-mood-questionnaire-from-the-antianxiety-food-solution/, https://www.everywomanover29.com/blog/amino-acids-pyroluria-supplements/, https://www.sciencedaily.com/releases/1998/08/980817081222.htm, https://pubmed.ncbi.nlm.nih.gov/20739874/, https://www.everywomanover29.com/blog/collagen-gelatin-lower-serotonin-increase-anxiety-depression/, https://pubmed.ncbi.nlm.nih.gov/17021603/, https://www.everywomanover29.com/blog/oxalate-crystal-disease-dietary-oxalates-and-pain-the-research-questions/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218441/, https://www.everywomanover29.com/blog/pharmagaba-vs-gaba-when-you-have-histamine-issues-mcas-does-pharmagaba-ease-physical-anxiety-or-make-things-worse/, https://www.jillcarnahan.com/2016/10/31/mast-cell-activation-syndrome-mcas-when-histamine-goes-haywire/, https://mastcell360.com/histamine-intolerance-vs-mast-cell-activation-syndrome/, Amino Acids Mood Questionnaire from The Antianxiety Food Solution, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, Pyroluria Questionnaire from The Antianxiety Food Solution, Tryptophan for the worry-in-your-head and ruminating type of anxiety, GABA for the physical-tension and stiff-and-tense-muscles type of anxiety, The Antianxiety Food Solution by Trudy Scott, Seriphos Original Formula is back: the best product for anxiety and insomnia caused by high cortisol, Am I an anxious introvert because of low zinc and vitamin B6? I tried and boy does it work! How much tryptophan is too much? - TimesMojo Approximately, how long would it take to clear the collagen from the system? windows terminal run powershell as admin; hydro flask flint shell; duniway hotel room service menu; aston apartments chicago Many thanks again! Collagen is found in your bones. As you age, your bones become less dense and more brittle, breaking more easily and taking longer to heal. attention span or sleep quality). But frankly, I have a lot of loose ends to tie up on my whole understanding of ginsenosides, before making an informed choice or recommendation. The so called "toxins in your brain" this reviewer is probably talking about is kynurenic acid, a byproduct or metabolite of L-Tryptophan when broken down by what he talks about, IDO. You are welcome and thank you for contributing to the discussion. The prescribing information for Lexapro specifically warns against the use of serotonin precursors like L-tryptophan: Serotonin Syndrome:Patients should be cautioned about the risk of serotonin syndrome with the concomitant use of Lexapro with other serotonergic drugs including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines and St. Johns Wort, and with drugs that impair metabolism of serotonin (in particular, MAOIs, both those intended to treat psychiatric disorders and also others, such as linezolid). I would want to figure out what the cause it and address it if possible (if its not an anaphalytic reaction) is low serotonin, oxalates, glutamates, arginine? MTHFR mutations are new to me so Im still learning. So how long does it take collagen supplements to work? Per the blog I have folks assess if low serotonin is a factor so they can continue with their collagen by also using tryptophan or 5-HTP. Increased muscle mass. If youre inflamed, collagen is going to make you feel better the next day. You can disbalance the number of amino acids leading to headaches, digestive issues, and fatigue. Pair Your Collagen With These Nutrients For Extra Oomph Can You Take Too Much Collagen? | Care/of - takecareof.com One of my three interviews on The Anxiety Summit 5: Gut-Brain Axisis: Collagen Can Cause Anxiety and Insomnia. Thats because that enzyme, indoleamine dioxygenase, IDO, burns up the tryptophan and 5-hydroxytryptophan. That means a person who weighs 154 pounds (or 70 kilograms) should get about 280 milligrams of tryptophan per day. Maintains skin elasticity. The only new supplement I took was the collagen. Collagen is important for the skin in a number of ways. I should also add that I tried collagen supplements again more recently this year, to help with nail growth, finding that I was OK with them for a week or so, but then noticed the symptoms of heart palpitations, dizziness, general anxiety, etc about two weeks after starting them again. For people struggling with mood disorders, insomnia or addictions, supplementing with 5HTP can be a good way to directly increase serotonin. But we're all different in our reactions, so just adding my 2 cents on mine. The mix will "cheat" and dodge the cytokines and go straight to your brain and knock you out! Also, I realize the collagen discussed in the Science Daily piece probably isnt supplemental collagen, but I am guessing there must be a connection? As a result, many people turn to collagen powder or other types of collagen supplements, such as capsules, gummies, and liquids. I recommend Lidtke tryptophan. Is Prozac Safe To Take With Birth Control Pills? However, supplementing with tryptophan led to a decrease of ADHD symptoms in children with ADHD. GABA doesn't pass the BBB so I take GABA boosters like L-Theanine and Taurine at bed every night and I take L-Theanine a lot during the day. Promotes whole-body healing Promotes joint health Replenishes cells Repairs digestive lining Promotes weight loss Builds muscle The Profound Effect of Collagen on Your Body Collagen makes up nearly one-third of the protein in your body (it's second only to water as your body's most common substance). I had no idea at first that there was a connection to the collagen supplements. Even now, I struggle here and there with some anxiety I didnt have before but I assume it takes some time for the brain to stop going down those pathways it learned. How to Take Collagen Protein (Plus Potential Side Effects) In the blog (https://www.everywomanover29.com/blog/collagen-gelatin-lower-serotonin-increase-anxiety-depression/) I share this for the serotonin solution do the low serotonin questionnaire and a trial of tryptophan (after checking the precautions) to see if this prevents this reaction when using collagen, Hello. This Steve Fowkes is a bit of a quack if you ask me but there's also a bit of truthiness to the things he says. It is easier to get higher doses with a single scoop of powder than it is to . NOTICED WITHIN A FEW WEEKS, NO SLEEP..WAKING UP AT 3 AM AND NOT DOING WELL. I'm using 120mg ginkgo, 150mg bacopa, 600mg ginseng, and 5g tea. If you eat enough calories in general, vary your intake of protein and plant foods, and arent dealing with an intestinal disorder, chances are that youre acquiring enough. I started taking collagen, and could not figure out why my anxiety went through the roof. If youre breastfeeding your baby may also start to sleep better once your serotonin levels rebound (assuming it is a serotonin issue). Tryptophan is very commonly added to collagen supplements in small amounts because collagen is an incomplete protein (i.e. Answered by Dr. Brian Staiger, PharmD When you lack collagen, your arteries may weaken. Hypothyroidism causes tryptophan levels to rise, which makes people suffering from hypothyroidism more hypothyroid. Generally, for improved skin and hair health, 2.5-10 grams of collagen peptides can be taken orally for 8-12 weeks daily. how much tryptophan to take with collagen Update! So I took 1000 mg and 15 to 20 minutes later I was telling my older teenaged son that I "felt like cleaning the stove and the fridge at the same time"! The unflavored has only 70 calories and 18g of protein, whereas the Chocolate and Vanilla have 130 to 140 calories, 3.5 to 4g of fat, 7g of carbs, and 19g of protein. Do Collagen Peptides Actually Work? - Cleveland Clinic I will never take collagen again. I noticed that I developed insomnia. More like 2 hours. Studies have found thattryptophan depletion worsens pain associated with tension headaches and migraines, plus can cause aggravated nausea and sleep problems experienced by many migraine sufferers. Ive had some PVCs my whole life (structurally normal heart, just annoying little buggers). One thing I've found gives a positive boost to l-tryptophan is to take it with a half teaspoon of honey and 500mg of flush free niacin on an empty stomach , but again that's just what's worked for me. The Best Times to Take Collagen: Facts Explained - Levels More here: Methylenetetrahydrofolate reductase and psychiatric diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218441/ Which mutations do you have? This would be a good question for Susan Ownens TLO/Trying Low Oxalates FB group, Do you know if this person also had dietary oxalate issues? Are there. They do so with tryptophan or 5-HTP or exercise or full spectrum light therapy. Giu 11, 2022 | narcissistic withdrawal. October 25, 2019 By Trudy Scott 78 Comments. Not sure what I can do about l-theanine withdrawal if that happens to me. Ann That low serotonin is bad, that you want it to be high because = happy hormone is a myth. I'm taking these as recommended by examine.com basically, although yeah maybe I won't take as much bacopa until it's more available. Matt I blamed it on worries over the pandemic.